FPL-62129 is a calcium channel antagonist for the treatment of hypertension and myocardia ischemia. FPL-62129 reduced blood pressure without altering heart rate. FPL 62129 showed marked activity at the sinus node and to a lesser extent at the atrioventricular node. Unlike nifedipine, FPL 62129 displays vasodilator and direct decelerator properties over the same dose range, which accounts for its ability to lower blood pressure without causing reflex tachycardia in this model. References: Humphries RG, O'Connor SE. Cardiovascular profile of FPL 62129, a novel dihydropyridine calcium channel blocker, in anaesthetised dogs: a comparison with nifedipine. J Cardiovasc Pharmacol. 1988 Mar;11(3):332-8. PubMed PMID: 2452927.

纯度：≥98%

CAS：95445-79-7