Piritrexim (BW-301U) is a methotrexate analog acting as an inhibitor of dihydrofolate reductase (DHFR). It lipid-soluble anti-folate with anticancer activity against metastatic urothelial tumors. As a synthetic antifolate agent, it exhibit antiparasitic, antipsoriatic and antitumor properties. Piritrexim inhibits the enzyme dihydrofolate reductase enzyme, thereby disrupting folate metabolism and DNA synthesis and cell division

纯度：≥98%

CAS：72732-56-0