tert-butyl 3-(4-(2-cyanoethynyl)phenylcarbamoyl)propylcarbamate is part of a new class of thiol-specific conjugation reagents consisting of a thiol-reactive 3-arylpropiolonitrile (APN) group. The APN group allows the targeted coupling of thiols in biomolecules, and results in stable thioether linkages without the risk of subsequent side reactions that can occur with maleimides. References: Badescu G, Bryant P, Swierkosz J, Khayrzad F, Pawlisz E, Farys M, Cong Y, Muroni M, Rumpf N, Brocchini S, Godwin A. A new reagent for stable thiol-specific conjugation. Bioconjug Chem. 2014 Mar 19;25(3):460-9. doi: 10.1021/bc400245v. Epub 2014 Feb 11. PubMed PMID: 24512057.

纯度：≥98%

CAS：1539292-60-8