FMK-9a is a novel, potent and covalent ATG4B (Autophagin-1) inhibitor with IC50 values of 80 and 73 μM in FRET and LRA assay. ATG4B or autophagin-1 is a cysteine protease that cleaves ATG8 family proteins. ATG4B plays essential roles in the autophagosome formation and the autophagy pathway.
纯度:≥98%
CAS:1955550-51-2