Tifenazoxide, formerly known as NN-414, is a K(ATP) channel opener (KCO). Tifenazoxide attenuates glucose sensing in hypothalamic GT1-7 neurons. References: Ma Z, Wirstrom T, Borg LA, Larsson-Nyrén G, Hals I, Bondo-Hansen J, Grill V, Bjorklund A. Diabetes reduces β-cell mitochondria and induces distinct morphological abnormalities, which are reproducible by high glucose in vitro with attendant dysfunction. Islets. 2012 May-Jun;4(3):233-42. doi: 10.4161/isl.20516. PubMed PMID: 22854606; PubMed Central PMCID: PMC3442821.
纯度:≥98%
CAS:279215-43-9