IBE-667 is an activator of LFA-1-ICAM-1 binding. References: Abdullahi M, Olotu FA, Soliman ME. Dynamics of allosteric modulation of lymphocyte function associated antigen-1 closure-open switch: unveiling the structural mechanisms associated with outside-in signaling activation. Biotechnol Lett. 2017 Dec;39(12):1843-1851. doi: 10.1007/s10529-017-2432-0. Epub 2017 Sep 16. PubMed PMID: 28918491.
纯度:≥98%