EM20-25 is a novel BCL-2 inhibitor, neutralizing the antiapoptotic activity of overexpressed BCL-2 toward staurosporine and sensitizing BCL-2-expressing cells from leukemic patients to the killing effects of staurosporine, chlorambucil, and fludarabine. References: Vasaikar SV, Ghosh S, Narain P, Basu A, Gomes J. HSP70 mediates survival in apoptotic cells-Boolean network prediction and experimental validation. Front Cell Neurosci. 2015 Aug 25;9:319. doi: 10.3389/fncel.2015.00319. eCollection 2015. PubMed PMID: 26379495; PubMed Central PMCID: PMC4548197.

纯度：≥98%

CAS：141266-44-6