您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > Trazium Esilate
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Trazium Esilate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:97110-59-3
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

Trazium esilate, formerly known as EGYT-3615, is an adrenergic receptor antagonist potentially for the treatment of major depressive disorder. Trazium esilate is a weak displacer on a1-, a2- and D2-receptors, however, it induced a2-receptor desenzitization after repeated treatment. It had no influence on rat brain cortical noradrenaline and striatal dopamine release evoked by high K+ concentration, but it increased the spontaneous dopamine outflow in rat striatum. References: Gyertyán I, Petocz L, Bajnógel J, Szücs Z, Hegedüs M, Gyüre K, Gacsályi I, Krizsán D, Fekete MI. Possible involvement of the dopaminergic system in the mode of action of the potential antidepressant trazium esilate. Arzneimittelforschung. 1989 Jul;39(7):775-81. PubMed PMID: 2551306.

纯度:≥98%

CAS:97110-59-3