BRD50837 is a potent and selective Sonic Hedgehog (Shh) inhibitor. The Hedgehog signaling pathway is involved in the development of multicellular organisms and, when deregulated, can contribute to certain cancers, among other diseases. References: Schaefer GI, Perez JR, Duvall JR, Stanton BZ, Shamji AF, Schreiber SL. Discovery of small-molecule modulators of the Sonic Hedgehog pathway. J Am Chem Soc. 2013 Jul 3;135(26):9675-80. doi: 10.1021/ja400034k. Epub 2013 Jun 25. PubMed PMID: 23725514; PubMed Central PMCID: PMC3703668.

纯度：≥98%

CAS：1314295-24-3