BRD9876 is a selective inhibitor of MM1S growth. It is selective for microtubule bound Eg5 and causes a rapid arrest in G2/M phase. References: Chen GY, Kang YJ, Gayek AS, Youyen W, Tüzel E, Ohi R, Hancock WO. Eg5 Inhibitors Have Contrasting Effects on Microtubule Stability and Metaphase Spindle Integrity. ACS Chem Biol. 2017 Apr 21;12(4):1038-1046. doi: 10.1021/acschembio.6b01040. Epub 2017 Feb 22. PubMed PMID: 28165699; PubMed Central PMCID: PMC5515541.
纯度:≥98%
CAS:32703-82-5