DK-139 is an inhibitor of NF-kappaB-mediated GROalpha expression, suppressing the TNFalpha-induced invasive capability of MDA-MB-231 human breast cancer cells. References: Gil HN, Koh D, Lim Y, Lee YH, Shin SY. The synthetic chalcone derivative 2-hydroxy-3',5,5'-trimethoxychalcone induces unfolded protein response-mediated apoptosis in A549 lung cancer cells. Bioorg Med Chem Lett. 2018 Jul 4. pii: S0960-894X(18)30554-7. doi: 10.1016/j.bmcl.2018.07.003. [Epub ahead of print] PubMed PMID: 30017320.
纯度:≥98%
CAS:1426059-23-5