Novokinin is an angiotensin AT2 receptor agonist. Novokinin exhibits vasorelaxing and hypotensive activity via activation of the IP (prostacyclin) receptor, and suppresses food intake via activation of PGE2-EP4 interaction. References: Pechlivanova D, Petrov K, Grozdanov P, Nenchovska Z, Tchekalarova J, Stoynev A. Intracerebroventricular infusion of an Angiotensin AT2 receptor agonist Novokinin aggravates some diabetes mellitus-induced alterations in Wistar rats. Can J Physiol Pharmacol. 2017 Oct 13. doi: 10.1139/cjpp-2017-0428. [Epub ahead of print] PubMed PMID: 29028440.
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CAS:358738-77-9