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Q-VD-OPh hydrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Q-VD-OPh hydrate图片
CAS NO:1135695-98-5
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍

生物活性

Q-VD-OPh hydrate是一种选择性,脑和细胞可渗透的,高效且不可逆的caspase-3(IC50 = 25nm),caspase-1(IC50 = 50nM),caspase-8(IC50 = 100nM)和caspase-9抑制剂 (IC50 = 430nM)。

靶点信息

Caspase-1Caspase-3Caspase-8Caspase-9
25 nM-400 nM25 nM-400 nM25 nM-400 nM25 nM-400 nM

化学数据

目录号A14915
作用机制Inhibitor (抑制剂)
M. Wt513.49
FormulaC26H25F2N3O6
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1135695-98-5
SMILESCC(C)C(C(=O)NC(CC(=O)O)C(=O)COC1=C(C=CC=C1F)F)NC(=O)C2=NC3=CC=CC=C3C=C2

溶解度

In vitroDMSO94 mg/mL (183.06 mM)
WaterInsoluble
Ethanol94 mg/mL (183.06 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM19.47 mL97.37 mL194.75 mL
0.5 mM3.89 mL19.47 mL38.95 mL
1 mM1.95 mL9.74 mL19.47 mL
5 mM0.39 mL1.95 mL3.89 mL

*The above data is based on the productmolecular weight 513.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.