Dihydrohomofolic acid is a substrate for dihydrofolate reductase; produces tetrahydrohomofolate which in turn inhibits thymidylate synthetase & therefore DNA synthesis. References: Mishra LC, Parmar AS, Mead JA. Effect of pretreatment with methotrexate on the reduction of dihydrohomofolic acid in mice. Biochem Pharmacol. 1971 Oct;20(10):2871-8. PubMed PMID: 5114519.

纯度：≥98%

CAS：14866-11-6