DETQ is a dopamine D1 receptor potentiator which induces a 21-fold leftward shift in the cAMP response to dopamine, with a Kb of 26 nM. References: Meltzer HY, Rajagopal L, Matrisciano F, Hao J, Svensson KA, Huang M. The allosteric dopamine D1 receptor potentiator, DETQ, ameliorates subchronic phencyclidine-induced object recognition memory deficits and enhances cortical acetylcholine efflux in male humanized D1 receptor knock-in mice. Behav Brain Res. 2018 Dec 3;36139-150. doi: 10.1016/j.bbr.2018.12.006. [Epub ahead of print] PubMed PMID: 30521930.
纯度:≥98%
CAS:1638667-81-8