C012 Dihydrochloride is a novel small molecule compound which sensitized BRAF wild-type melanoma cells to vemurafenib. C012 Dihydrochloride significantly reduced melanoma cell viability, with limited toxicity for normal human fibroblasts. References: Sutton SK, Carter DR, Kim P, et al. A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner. Oncotarget. 2016;7(32):52166-52178. doi:10.18632/oncotarget.10700.
纯度:≥98%
CAS:1219163-50-4