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Dabigatran etexilate mesylate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dabigatran etexilate mesylate图片
CAS NO:872728-81-9
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议

产品名称
Pradaxa, BIBR 1048MS, Dabigatran etexilate methanesulfonate
产品介绍

生物活性

Dabigatran etexilate mesylate是达比加群的口服活性前药。达比加群是一种可逆的选择性直接凝血酶抑制剂(DTI),Ki值为4.5 nM。

化学数据

目录号A15057
作用机制Inhibitor (抑制剂)
M. Wt723.84
FormulaC35H45N7O8S
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.872728-81-9
SynonymsPradaxa, BIBR 1048MS, Dabigatran etexilate methanesulfonate
SMILESCCCCCCOC(=O)N=C(C1=CC=C(C=C1)NCC2=NC3=C(N2C)C=CC(=C3)C(=O)N(CCC(=O)OCC)C4=CC=CC=N4)N.CS(=O)(=O)O

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM13.82 mL69.08 mL138.15 mL
0.5 mM2.76 mL13.82 mL27.63 mL
1 mM1.38 mL6.91 mL13.82 mL
5 mM0.28 mL1.38 mL2.76 mL

*The above data is based on the productmolecular weight 723.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.