CU239 is a selective non-retinoid inhibitor of RPE65 which suppresses visual cycle and prevents retinal degeneration. References: Shin Y, Moiseyev G, Petrukhin K, Cioffi CL, Muthuraman P, Takahashi Y, Ma JX. A novel RPE65 inhibitor CU239 suppresses visual cycle and prevents retinal degeneration. Biochim Biophys Acta Mol Basis Dis. 2018 Jul;1864(7):2420-2429. doi: 10.1016/j.bbadis.2018.04.014. Epub 2018 Apr 21. PubMed PMID: 29684583; PubMed Central PMCID: PMC5963526.
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CAS:946249-82-7