Cgp 29030A is a novel piperazine analogue that has marked inhibitory action on presumably nociceptive dorsal horn neurons that processed input from high-threshold mechanosensitive receptors in the skin and deep somatic tissues (muscle, tendon, joint). It may be of benefit in the treatment of painful disorders which are complicated by increased motor activity. References: Yu XM, Hoheisel U, Mense S. Effects of a novel piperazine derivative (CGP 29030A) on nociceptive dorsal horn neurons in the rat. Drugs Exp Clin Res. 1992;18(11-12):447-59. PubMed PMID: 1308469.
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CAS:113240-27-0