Cgp 43182 is a potent inhibitor of group IIA secreted phospholipase A2 (group IIA sPLA2) activity in vitro. Cgp 43182 is a potent anti-inflammatory drug useful for preventing the consequences of a concerted action of cytokine-stimulated pro-inflammatory genes mediated by NFkappaB. References: Kumar KN, Johnson PS, Chen X, Pal R, Ahmad M, Ragland T, Bigge C, Michaelis EK. Cloning of a brain N-methyl-D-aspartate- and D, L-epsilon-2-amino-4-propyl-5-phosphono-3-pentanoic acid (CGP 39653)-binding protein. Biochem Biophys Res Commun. 1998 Dec 18;253(2):463-9. PubMed PMID: 9878559.

纯度：≥98%

CAS：150379-37-6