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Crinecerfont(SSR125543)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Crinecerfont(SSR125543)图片
CAS NO:752253-39-7
规格:≥98%
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议

产品介绍
Crinecerfont (SSR-125543) is a highly potent, selective, and orally bioavailable antagonist of corticotropin-releasing factor 1 receptor (CRF1) with pKis of 8.73 and 9.08 for human cloned or native CRF1 receptors, respectively. SSR125543 attenuates long-term cognitive deficit induced by acute inescapable stress in mice, independently from the hypothalamic pituitary adrenal axis. SSR125543 prevents stress-induced cognitive deficit associated with hippocampal dysfunction.