CO-102862, formerly known as V102862, is a potent, broad-spectrum state-dependent blocker of mammalian voltage-gated sodium channels. It is an orally bioavailable anticonvulsant with robust activity in a variety of rodent models of epilepsy. References: Ilyin VI, Hodges DD, Whittemore ER, Carter RB, Cai SX, Woodward RM. V102862 (Co 102862): a potent, broad-spectrum state-dependent blocker of mammalian voltage-gated sodium channels. Br J Pharmacol. 2005 Mar;144(6):801-12. PubMed PMID: 15778702; PubMed Central PMCID: PMC1576061.
纯度:≥98%
CAS:181144-66-1