Clomifene (also known as NSC 35770; Clomiphene) is a potent SERM
(selective estrogen receptor modulator) which is used in the treatment of
ovulation induction. It acts by inhibiting the action of estrogen on the
pituitary. Clomiphene Citrate is an activator of PKC. Clomifene
competes with [3H]-QNB and [3H]-nitrendipine for their binding to the
receptor in the membrane fractions from the urinary bladder and
myometrium. Clomifene inhibits estrogen receptors in the hypothalamus,
inhibiting negative feedback of estrogen on gonadotropinrelease.
纯度:≥98%
CAS:911-45-5