CL67 is an inhibitor of the hypoxia-inducible factor pathway. It acts by binding to a G-quadruplex higher-order structure in the HIF promoter sequence in vitro. References: Welsh SJ, Dale AG, Lombardo CM, Valentine H, de la Fuente M, Schatzlein A, Neidle S. Inhibition of the hypoxia-inducible factor pathway by a G-quadruplex binding small molecule. Sci Rep. 2013 Sep 30;3:2799. doi: 10.1038/srep02799. PubMed PMID: 24165797; PubMed Central PMCID: PMC3810677.
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CAS:1401242-86-1