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Propionyl coenzyme A lithium
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Propionyl coenzyme A lithium图片
CAS NO:108321-21-7
包装:5mg
市场价:3713元

产品介绍
Propionyl coenzyme A lithium，丙酸的辅酶 A 衍生物, 是由辅酶 A 与丙酸通过硫酯键结合成的重要代谢中间产物。 Propionyl coenzyme A lithim 的分解和产生对生物体代谢具有重要的意义。
Cas No.108321-21-7
分子式C24H40LiN7O17P3S
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Propionyl coenzyme A lithium, a coenzyme A derivative of propionic acid, is an important metabolic intermediate formed by the thioester bond between coenzyme A and propionic acid. The breakdown and production of Propionyl coenzyme A lithim is important for the metabolism of organisms[1][2].

Propionyl coenzyme A lithium causes toxic effects due to its accumulation and the impact of its metabolism on cell wall synthesis and maintenance inMycobacterium tuberculosis[1].
Propionyl coenzyme A lithium can be converted to β-hydroxypropionic acid via a peroxisomal enzyme-modified β-oxidation pathway inArabidopsis[2].
Propionyl coenzyme A lithium causes the formation of propionic acidemia due to its abnormal accumulation, which often occurs in the neonatal developmental stage[3].

[1]. Ernesto J MuÑoz-ElÍas, et al. Role of the methylcitrate cycle in Mycobacterium tuberculosis metabolism, intracellular growth, and virulence. Mol Microbiol. 2006 Jun;60(5):1109-22.
[2]. Kerry A Lucas, et al. Peroxisomal metabolism of propionic acid and isobutyric acid in plants. J Biol Chem. 2007 Aug 24;282(34):24980-9.
[3]. Oleg A Shchelochkov, et al. Propionic Acidemia. 2012 May 17 [updated 2016 Oct 6]. In: Adam MP, Everman DB, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1