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(E/Z)-Sulindac sulfide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(E/Z)-Sulindac sulfide图片
CAS NO:32004-67-4
包装:25mg
市场价:1839元

产品介绍
(E/Z)-Sulindac sulfide 是一种有效的 γ-secretase 调节剂。(E/Z)-Sulindac sulfide 可选择性地减少 Aβ42 产生,有利于更短的 Aβ 类型的产生。(E/Z)-Sulindac sulfide 可用于阿尔兹海默症的研究。
Cas No.32004-67-4
分子式C20H17FO2S
分子量340.41
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(E/Z)-Sulindac sulfide is a potentγ-secretasemodulator (GSM). (E/Z)-Sulindac sulfide selectively reduces Aβ42 production in favor of shorterspecies. (E/Z)-Sulindac sulfide can be used for researching Alzheimer's disease[1].

[1]. Richter L, et al. Amyloid beta 42 peptide (Abeta42)-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerization. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14597-602.