| CAS NO: | 892772-75-7 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| Cas No. | 892772-75-7 |
| 分子式 | C19H15N3O2S |
| 分子量 | 349.41 |
| 储存条件 | 4°C, away from moisture and light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | EAI001 is a potent, selective mutantepidermal growth factor receptor (EGFR)allosteric inhibitor with anIC50value of 24 nM for EGFRL858R/T790M. EAI001 can be used for research of cancer[1][2]. EAI001 (50 μM) binds to EGFR T790M/C797S/V948R that lies deep inside the EGFR towards the ATP binding site and C-helix. EAI001 showed inhibitory activity due to hydrophobic interaction with amino acid Ile759, Leu747, Leu788, Leu777 and Met766[1]. |
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