CAS NO: | 2359649-81-1 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
Cas No. | 2359649-81-1 |
分子式 | C21H21FN6O3 |
分子量 | 424.43 |
溶解度 | DMSO : 100 mg/mL (235.61 mM; ultrasonic and warming and heat to 80°C) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Enbezotinib, an inhibitor of RET, can inhibit the RET autophosphorylation. Enbezotinib can be used for the research of cancer[1]. Enbezotinib (compound 5) (0.3-300 nM) inhibits p-RET (y905) in RET-driven cells[1]. Enbezotinib (compound 5) (2-5 mg/kg; twice daily for 27 days) decreases tumor size in mice[1]. [1]. ROGERS EW, et, al. Macrocyclic compounds for treating disease. WO2019126121A1. |