PF-06685249 (PF-249) 是一种有效的、具有口服活性的变构 AMPK 激活剂，对重组 AMPK α1β1γ1 的 EC50 为 12 nM。PF-06685249 可用于糖尿病肾病研究。
| Cas No. | 1467059-70-6 |
| 别名 | PF-249 |
| 分子式 | C17H16ClN3O3 |
| 分子量 | 345.78 |
| 溶解度 | DMSO : 100 mg/mL (289.20 mM; Need ultrasonic) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | PF-06685249 (PF-249) is a potent and orally active allostericAMPKactivator with anEC50of 12 nM for recombinant AMPK α1β1γ1. PF-06685249 can be used for diabetic nephropathy research[1]. |
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