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Batatasin III
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Batatasin III图片
CAS NO:56684-87-8
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
Batatasin III 是一种芪类化合物,通过抑制上皮间质转化 (EMT) 和FAK-AKT 信号来抑制癌症迁移和侵袭。Batatasin III 具有抗癌活性。
Cas No.56684-87-8
别名山药素Ⅲ
分子式C15H16O3
分子量244.29
储存条件4°C, away from moisture and light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Batatasin III, a stilbenoid, inhibits cancer migration and invasion by suppressing epithelial to mesenchymal transition (EMT) and FAK-AKT signals. Batatasin III has anti-cancer activities[1].

Batatasin III (25-100 μM; 48 h) exhibits anti-proliferative activity in H460 cells. Batatasin III at concentrations lower than 100 μM has no cytotoxic effects[1]. Batatasin III significantly suppresses EMT indicated by the decrease of N-cadherin and Vimentin, and up-regulation of E-cadherin[1].

[1]. Tatchakorn Pinkhien, et al. Batatasin III Inhibits Migration of Human Lung Cancer Cells by Suppressing Epithelial to Mesenchymal Transition and FAK-AKT Signals. Anticancer Res. 2017 Nov;37(11):6281-6289.