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2'-Deoxy-5'-O-DMT-2'-fluorouridine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
2'-Deoxy-5'-O-DMT-2'-fluorouridine图片
CAS NO:146954-74-7
包装与价格:
包装价格(元)
5g电议
25g电议

产品介绍
2'-Deoxy-5'-O-DMT-2'-fluorouridine 是一种核苷类似物,是 5'-O-DMTr-5-FUDR 的衍生物。2'-Deoxy-5'-O-DMT-2'-fluorouridine 具有有效的抗黄热病 (YFV) 活性。
Cas No.146954-74-7
分子式C30H29FN2O7
分子量548.56
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5'-O-DMTr-5-FUDR derivative with potentanti-yellow fever (YFV)activity[1].

2'-Deoxy-5'-O-DMT-2'-fluorouridine (compound 15h) has 100% inhibition against YFV at 20 mM. 2'-Deoxy-5'-O-DMT-2'-fluorouridine proves to be noncytotoxic at concen-trations up to 20 mM[1].

[1]. Christopher McGuigan, et al. Anti-flavivirus Activity of Different Tritylated Pyrimidine and Purine Nucleoside Analogues. ChemistryOpen. 2016 Jan 21;5(3):227-35.