| 包装 | 价格(元) |
| 10mg | 电议 |
| 50mg | 电议 |
| Canonical SMILES | FC1=CC=CC=C1CNCC(C=C4)=CC=C4C2=C3C(NC=C3)=NC=C2.Cl.Cl |
| 分子式 | C21H18FN3.2HCl |
| 分子量 | 404.31 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Potent ROCK inhibitor (IC50 = 10 nM). Suppresses pMYPT1 and pCofilin levels in non-small cell lung carcinoma (NSCLC) cell lines. Also inhibits anchorage-independent growth of NSCLC cell lines in vitro. Vigil et al (2012) ROCK1 and ROCK2 are required for non-small cell lung cancer anchorage-independent growth and invasion. Cancer Res. 72 5338 PMID:22942252 |
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