ω-Conotoxin GVIA, a peptide compound, is a neurotoxin that acts as a potent antagonist of voltage-activated N-type Ca²⁺ channels and of neurotransmitter release at neuronal synapses. Its antagonistic activity is attributed to a tyrosine residue at position 13. Does not bind to dihydropyridine- or verapamil-binding sites. Also reported to inhibit ATP-induced inward currents mediated by P2X2/X3 receptors (IC₅₀ = 21.2 nM for P2X3 and 3.84 μM for P2X2/X3 heterooligomeric receptors).

纯度：≥98%

CAS：106375-28-4