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5-hydroxy Indole-3-acetic Acid-d6
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
5-hydroxy Indole-3-acetic Acid-d6图片
CAS NO:2748469-82-9
包装与价格：
包装价格(元)
500 µg电议
1mg电议
5mg电议

产品介绍
An internal standard for the quantification of 5-hydroxy indole-3-acetic acid
Cas No.2748469-82-9
Canonical SMILESOC(C([2H])([2H])C(C1=C2[2H])=C([2H])NC1=C([2H])C([2H])=C2O)=O
分子式C10H3D6NO3
分子量197.2
溶解度DMSO: soluble,Ethyl Acetate: soluble,Methanol: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

5-hydroxy Indole-3-acetic acid-d6(5-HIAA-d6) is intended for use as an internal standard for the quantification of 5-HIAA by GC- or LC-MS. 5-HIAA is a metabolite of the monoamine neurotransmitter serotonin .1It is formed from serotoninviaa 5-hydroxy indole-3-acetaldehyde intermediate by aldehyde dehydrogenase. 5-HIAA has been used as a biomarker for the detection of neuroendocrine tumors. Brain levels of 5-HIAA are decreased in patients with severe Alzheimer's disease.2

1.Corcuff, J.-B., Chardon, L., El Hajji Ridah, I., et al.Urinary sampling for 5HIAA and metanephrines determination: Revisiting the recommendationsEndocr. Connect.6(6)R87-R98(2017) 2.Vermeiren , Y., Van Dam, D., Aerts, T., et al.Monoaminergic neurotransmitter alterations in postmortem brain regions of depressed and aggressive patients with Alzheimer's diseaseNeurobiol. Aging35(12)2691-2700(2014)