| CAS NO: | 57449-30-6 |
| 包装: | 1mg |
| 市场价: | 11550元 |
| Cas No. | 57449-30-6 |
| Canonical SMILES | CC=CC(OCC1=C[C@@H](O)[C@@H](O)[C@@H](O)C1=O)=O |
| 分子式 | C11H14O6 |
| 分子量 | 242.2 |
| 溶解度 | DMSO: soluble,Methanol: soluble,Water: soluble |
| 储存条件 | -20буC |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | COTC is a bacterial metabolite that has been found inS. griseosporeusand has anticancer activity.1It inhibits glyoxalase in the presence of glutathione (GSH) in a concentration- and time-dependent manner. COTC inhibits the proliferation of HeLa cells (IC50= 18 µg/ml), as well as reduces tumor growth and improves survival in an Ehrlich murine spontaneous adenocarcinoma model. 1.Takeuchi, T., Chimura, H., Hamada, M., et al.A glyoxalase I inhibitor of a new structural type produced by StreptomycesJ. Antibiot. (Tokyo)28(1)737-742(1975) |
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