| 包装 | 价格(元) |
| 500 µg | 电议 |
| 1mg | 电议 |
| 5mg | 电议 |
| Canonical SMILES | NC1=NC([O-])=C2[N+](C([2H])([2H])[2H])=CN([C@@]3([H])[C@H](O)[C@H](O)[C@@H](CO)O3)C2=N1 |
| 分子式 | C11H12D3N5O5 |
| 分子量 | 300.3 |
| 溶解度 | 0.1 M HCl: 10mg/mL,DMSO: 10mg/mL |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 7-Methylguanosine-d3is intended for use as an internal standard for the quantification of 7-methylguanosine by GC- or LC-MS. 7-Methylguanosine is a methylated form of the purine nucleoside guanosine . It is an RNA modification that is present in the 5’-terminal cap of mRNA, where it promotes translation, as well as in tRNA, where it stabilizes the tRNA structure.1,27-Methylguanosine has been used as a substrate to measure the activity of purine nucleoside phosphorylase (PNP).3Urinary 7-methylguanosine levels are decreased in patients with prostate cancer.1 1.FernÁndez-Peralbo, M.A., GÓmez-GÓmez, E., CalderÓn-Santiago, M., et al.Prostate cancer patients-negative biopsy controls discrimination by untargeted metabolomics analysis of urine by LC-QTOF: Upstream information on other omicsSci. Rep.638243(2016) 2.Tomikawa, C.7-Methylguanosine modifications in transfer RNA (tRNA)Int. J. Mol. Sci.19(12)4080(2018) 3.Stachelska-Wierzchowska, A., and Wierzchowski, J.Non-typical nucleoside analogs as fluorescent and fluorogenic indicators of purine-nucleoside phosphorylase activity in biological samplesAnal. Chim. Acta1139119-128(2020) |
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