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N-Acetyl-L-thyroxine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
N-Acetyl-L-thyroxine图片
CAS NO:26041-51-0
包装与价格：
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
A thyroid hormone derivative
Cas No.26041-51-0
别名N-乙酰基L-甲状腺素
Canonical SMILESIC1=CC(C[C@@H](C(O)=O)NC(C)=O)=CC(I)=C1OC2=CC(I)=C(C(I)=C2)O
分子式C17H13I4NO5
分子量818.9
溶解度DMF: 14 mg/mL,DMSO: 25 mg/mL,Ethanol: 20 mg/mL,PBS (pH 7.2): 0.2 mg/mL
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N-Acetyl-L-thyroxine is an acetylated derivative of L-thyroxine .1It only weakly binds to thyroxine-binding globulin (TBG) in isolated human serum with a relative binding affinity of 25 compared with L-thyroxine. N-Acetyl-L-thyroxine is also a potential impurity in commercial preparations of L-thyroxine.2

1.Snyder, S.M., Cavalieri, R.R., Goldfine, I.D., et al.Binding of thyroid hormones and their analogues to thyroxine-binding globulin in human serumJ. Biol. Chem.251(21)6489-6494(1976) 2.Panmanad, D., Joshi, M.S., Patil, R., et al.Synthesis and characterization of potential impurities in levothyroxineChem. Sci. Trans.5(4)1082-1089(2016)