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Sauvagine(trifluoroacetate salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
包装与价格:
包装价格(元)
500 µg电议
1mg电议

产品介绍
A neuropeptide hormone
Canonical SMILESOC(C(F)(F)F)=O.CC[C@H](C)[C@@H](C(N)=O)NC([C@H]([C@H](O)C)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CC(N)=O)NC([C@H](CC(N)=O)NC([C@H](C)NC([C@H](C)NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@H](CCCCN)NC([C@H](CCC(O)=O)NC([C@H](CCCCN)NC([C@H](CCC(O)=O)NC([C@H](CCC(N)=O)NC([C@H](CCCCN)NC([C@H](CCC(O)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CCC(O)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CCSC)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCC(O)=O)NC([C@H](CC(C)C)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@H](CC(O)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CO)NC([C@H]([C@@H](C)CC)NC([C@H]1N(C([C@H]2N(C(CNC([C@H](CC3)NC3=O)=O)=O)CCC2)=O)CCC1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
分子式C202H346N56O63S • XCF3COOH
分子量4599.4
溶解度Water: soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Sauvagine is a neuropeptide hormone that has been found in frog (P. sauvagei) skin and member of the corticotropin-releasing factor (CRF) family, which includes mammalian CRF , urocortin , urocortin II , urocortin III , and piscine urotensin 1.1,2In vivo, sauvagine (0.5 µg/kg, s.c.) reduces systemic blood pressure in normotensive rats.2It inhibits anterior pituitary release of prolactin, thyroid-stimulating hormone (TSH), and growth hormone in rats. Sauvagine also increases plasma adrenocorticotropic hormone (ACTH) levels in rats.3

1.AdÃo, R., Santos-Ribeiro, D., Rademaker, M.T., et al.Urocortin 2 in cardiovascular health and diseaseDrug Discov. Today20(7)906-914(2015) 2.Montecucchi, P.C., and Henschen, A.Amino acid composition and sequence analysis of sauvagine, a new active peptide from the skin of Phyllomedusa sauvageiInt. J. Pept. Protein Res.18(2)113-120(1981) 3.Rivier, C., Rivier, J., Lederis, K., et al.In vitro and in vivo ACTH-releasing activity of ovine CRF, sauvagine and urotensin IRegul. Pept.5(2)139-143(1983)