您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > Phenacetin-d5
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Phenacetin-d5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Phenacetin-d5图片
CAS NO:69323-74-6
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
Phenacetin-d5 (Acetophenetidin-d5) 是 Phenacetin 的氘代物。Phenacetin (Acetophenetidin) 是一种非阿片类解热化合物,可用于缓解疼痛的研究。Phenacetin 是一种选择性的 COX-3 抑制剂。Phenacetin 能作为人肝微粒体和大鼠体内 CYP1A2 的探针。
Cas No.69323-74-6
别名Acetophenetidin-d5
分子式C10H8D5NO2
分子量184.25
溶解度DMSO : 100 mg/mL (542.74 mM; ultrasonic and warming and heat to 60°C)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Phenacetin-d5 (Acetophenetidin-d5) is the deuterium labeled Phenacetin. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selectiveCOX-3inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats[1][2][3].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].