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TCS PIM-1 1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
TCS PIM-1 1图片
CAS NO:491871-58-0
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议

产品名称
SC 204330, TCS PIM 1-1
产品介绍

生物活性

TCS PIM-1 1是一种有效的且具有选择性的ATP竞争性Pim-1 kianse抑制剂,IC50为50 nM,对Pim-2和MEK1/MEK2表现出良好的选择性(IC50s> 20,000 nM)。

化学数据

目录号A15369
作用机制Inhibitor (抑制剂)
M. Wt367.2
FormulaC18H11BrN2O2
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.491871-58-0
SynonymsSC 204330, TCS PIM 1-1
SMILESC1=CC=C(C=C1)C2=C(C(=O)NC(=C2)C3=C(C=CC(=C3)Br)O)C#N

溶解度

In vitroDMSO70 mg/mL (190.63 mM)
Water<1 mg/mL
Ethanol<1 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM27.23 mL136.17 mL272.33 mL
0.5 mM5.45 mL27.23 mL54.47 mL
1 mM2.72 mL13.62 mL27.23 mL
5 mM0.54 mL2.72 mL5.45 mL

*The above data is based on the productmolecular weight 367.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.