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RGD peptide(GRGDNP)TFA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
RGD peptide(GRGDNP)TFA图片
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
50mg电议

产品介绍
RGD peptide (GRGDNP) (TFA)作为整合素-配体相互作用的抑制剂,在细胞黏附、迁移、生长和分化中发挥重要作用。RGD peptide (GRGDNP) (TFA)通过激活构象变化促进细胞凋亡,从而增强caspase-3的活化。
分子式C25H39F3N10O12
分子量728.63
溶解度Water: ≥ 50 mg/mL (68.62 mM); DMSO: ≥ 50 mg/mL (68.62 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

RGD peptide (GRGDNP) (TFA) acts as an inhibitor of integrin-ligand interactions and plays an important role in cell adhesion, migration, growth, and differentiation[1]. RGD peptide (GRGDNP) (TFA) promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing[2][3].

[1]. Ruoslahti, E., and Öbrink, B. Common principles in cell adhesion Experimental Cell Research 227, 1-11 (1996). [2]. Meredith JE Jr, et al. Integrins, adhesion and apoptosis. Trends Cell Biol. 1997 Apr;7(4):146-50. [3]. Yang W, et al. Activation of the Cdc42-associated tyrosine kinase-2 (ACK-2) by cell adhesion via integrin beta1. J Biol Chem. 1999 Mar 26;274(13):8524-30.