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b-AP15(NSC 687852)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
b-AP15(NSC 687852)图片
CAS NO:1009817-63-3
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议

产品名称
B-AP15
产品介绍

生物活性

b-AP15 (NSC 687852)是两种与蛋白酶体相关的DUBs的泛素特异性加工蛋白酶14(USP14)和泛素羧基末端水解酶同工酶L5(UCHL5)的抑制剂。

靶点信息

USP14UCHL5
N/A2.1 μM

化学数据

目录号A15391
作用机制Inhibitor (抑制剂)
M. Wt419.39
FormulaC22H17N3O6
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1009817-63-3
Synonymsb-AP15
SMILESC=CC(=O)N1CC(=CC2=CC=C(C=C2)[N+](=O)[O-])C(=O)C(=CC3=CC=C(C=C3)[N+](=O)[O-])C1

溶解度

In vitro (25°C)DMSOWarmed: 42 mg/mL (100.14 mM)
WaterInsoluble
EthanolInsoluble
In vivo4% DMSO+corn oil1 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM23.84 mL119.22 mL238.44 mL
0.5 mM4.77 mL23.84 mL47.69 mL
1 mM2.38 mL11.92 mL23.84 mL
5 mM0.48 mL2.38 mL4.77 mL

*The above data is based on the productmolecular weight 419.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.