(±)-SDZ-201 106 (SDZ 201106) 是一种强心剂，具有协同肌膜和细胞内作用机制。
| Cas No. | 97730-95-5 |
| 别名 | SDZ 201106 |
| Canonical SMILES | OC(COC1=CC=CC2=C1C=C(C#N)N2)CN(CC3)CCN3C(C4=CC=CC=C4)C5=CC=CC=C5 |
| 分子式 | C29H30N4O2 |
| 分子量 | 466.6 |
| 溶解度 | DMF: 30 mg/mL,DMSO: 30 mg/mL,Ethanol: 1.6 mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | (±)-SDZ-201 106 is a diphenylpiperazinylindole derivative that prolongs the open state of cardiac voltage-gated Na+ channels. It has been shown to increase net Na+ influx and the activity of reverse mode Na+/Ca2+ exchange, which leads to an increase in intracellular Ca2+, as well as to partially inhibit the Na+ pump in cardiac myocytes. (±)-SDZ-201 106 is also reported to act as an open-channel blocker of delayed-rectifier K+ channels in NG108-15 neuronal cells. |
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