包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
别名 | L-异亮氨酸 15N,d10 |
分子式 | C6H3D1015NO2 |
分子量 | 142.23 |
溶解度 | Water : 25 mg/mL (175.77 mM; ultrasonic and warming and heat to 60℃) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | L-Isoleucine-15N,d10 is the deuterium and 15N-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |