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SNX-0723
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SNX-0723图片
CAS NO:1073969-18-2
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
SNX-0723 是一种 Hsp90 抑制剂,具有抗疟原虫活性。SNX-0723 对 HsHsp90 和 PfHsp90 具有高结合亲和力,Ki 分别为 4.4 和 47 nM。SNX-0723 抑制肝期伯氏疟原虫 ANKA 寄生虫,EC50 为 3.3 μM。
Cas No.1073969-18-2
分子式C22H26FN3O3
分子量399.46
溶解度DMSO : 20.83 mg/mL (52.15 mM; ultrasonic and warming and heat to 60℃)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

SNX-0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity. SNX-0723 shows high binding affinity for HsHsp90 and PfHsp90 with Kis of 4.4 and 47 nM, respectively. SNX-0723 inhibits liver-stage P. berghei ANKA parasites with the EC50 of 3.3 μM[1].

[1]. Dora Posfai, et al. Identification of Hsp90 Inhibitors with Anti-Plasmodium Activity. Antimicrob Agents Chemother. 2018 Mar 27;62(4):e01799-17.