CAS NO: | 144449-71-8 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
Cas No. | 144449-71-8 |
别名 | 多非利特氮氧化物,UK-116856 |
Canonical SMILES | O=N(CCOC1=CC=C(NS(=O)(C)=O)C=C1)(CCC2=CC=C(NS(=O)(C)=O)C=C2)C |
分子式 | C19H27N3O6S2 |
分子量 | 457.6 |
溶解度 | DMF: insol,DMSO: 1 mg/ml,Ethanol: insol,PBS (pH 7.2): insol |
储存条件 | -20буC |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Dofetilide N-oxide is a metabolite of the antiarrhythmic agent dofetilide .1It prolongs intracellular action potential duration in isolated guinea pig papillary muscle, as a measure of antiarrhythmic activity, less potently than dofetilide. 1.Walker, D.K., Alabaster, C.T., Congrave, G.S., et al.Significance of metabolism in the disposition and action of the antidysrhythmic drug, dofetilide. In vitro studies and correlation with in vivo dataDrug Metab. Dispos.24(4)447-455(1996) |