CAS NO: | 84467-94-7 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
Cas No. | 84467-94-7 |
别名 | N-去甲盐酸西布曲明,N-Desmethylsibutramine hydrochloride |
Canonical SMILES | ClC1=CC=C(C2(C(CC(C)C)NC)CCC2)C=C1.Cl |
分子式 | C16H24ClN • HCl |
分子量 | 302.3 |
溶解度 | Water: soluble |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Desmethyl sibutramine is an active metabolite of sibutramine.1It prevents reserpine-induced ptosis in rats (ED50= 4.2 mg/kg) and decreases immobility in the Porsolt learned helplessness test in mice when administered at a dose of 10 mg/kg. 1.Luscombe, G.P., Hopcroft, R.H., Tomas, P.C., et al.The contribution of metabolites to the rapid and potent down-regulation of rat cortical β-adrenoceptors by the putative antidepressant sibutramine hydrochlorideNeuropharmacology28(2)129-134(1989) |