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4-oxo Cyclophosphamide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
4-oxo Cyclophosphamide图片
CAS NO:27046-19-1
包装与价格:
包装价格(元)
500 µg电议
1mg电议

产品介绍
An inactive metabolite of cyclophosphamide
Cas No.27046-19-1
Canonical SMILESO=C1NP(OCC1)(N(CCCl)CCCl)=O
分子式C7H13Cl2N2O3P
分子量275.1
溶解度DMSO: slightly soluble,Methanol: slightly soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

4-oxo Cyclophosphamide is an inactive metabolite of the alkylating agent cyclophosphamide .1,2It is formed from cyclophosphamide through a 4-hydroxycyclophosphamide intermediate by aldehyde dehydrogenases.2

1.Struck, R.F., Kirk, M.C., Mellett, L.B., et al.Urinary metabolites of the antitumor agent cyclophosphamideMol. Pharmacol.7(5)519-529(1971) 2.de Jonge, M.E., Huitema, A.D.R., Rodenhuis, S., et al.Clinical pharmacokinetics of cyclophosphamideClin. Pharmacokinet.44(11)1135-1164(2005)