| CAS NO: | 3384-24-5 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| Cas No. | 3384-24-5 |
| 别名 | 9-羟基十八酸 |
| Canonical SMILES | OC(CCCCCCCC(O)CCCCCCCCC)=O |
| 分子式 | C18H36O3 |
| 分子量 | 300.5 |
| 溶解度 | Chloroform: soluble |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 9-hydroxy Stearic acid is a hydroxy fatty acid and an active metabolite of 9-PAHSA .1,2It is formed from 9-PAHSA by liver and pancreatic carboxyl ester lipases.29-hydroxy Stearic acid (5 µM) inhibits histone deacetylase 1 (HDAC1) in HT-29 colon cancer cell lysates.3It inhibits the proliferation of, and induces cell cycle arrest at the G0/G1phase in, HT-29 cells when used at a concentration of 100 µM.1 1.Calonghi, N., Cappadone, C., Pagnotta, E., et al.9-Hydroxystearic acid upregulates p21WAF1 in HT29 cancer cellsBiochem. Biophys. Res. Commun.314(1)138-142(2004) 2.Kolar, M.J., Kamat, S.S., Parsons, W.H., et al.Branched fatty acid esters of hydroxy fatty acids are preferred substrates of the MODY8 protein carboxyl ester lipaseBiochemistry55(33)4636-4641(2016) 3.Calonghi, N., Cappadone, C., Pagnotta, E., et al.Histone deacetylase 1: A target of 9-hydroxystearic acid in the inhibition of cell growth in human colon cancerJ. Lipid Res.46(8)1596-1603(2005) |
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