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2′-Deoxyuridine-d2
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
2′-Deoxyuridine-d2图片
CAS NO:40632-23-3
包装与价格：
包装价格(元)
1mg电议
5mg电议

产品介绍
An internal standard for the quantification of 2’-deoxyuridine
Cas No.40632-23-3
别名2'-脱氧尿苷-5,6-D2
Canonical SMILESOC[C@H]1O[C@](N2C(NC(C([2H])=C2[2H])=O)=O)([H])C[C@@H]1O
分子式C9H10D2N2O5
分子量230.2
溶解度DMF: 16 mg/mL,DMSO: 10mg/mL,Ethanol: slightly soluble,PBS (pH 7.2): 5mg/mL
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2’-Deoxyuridine-d2is intended for use as an internal standard for the quantification of 2’-deoxyuridine by GC- or LC-MS. 2’-Deoxyuridine is a pyrimidine nucleoside composed of the pyrimidine base uracil attached to the sugar deoxyribose.1It has been used as a precursor in the synthesis of antiviral deoxyuridine derivatives, including idoxuridine .2,3Formulations containing 2’-deoxyuridine have been used in the deoxyuridine suppression test to identify vitamin B12 and/or folate deficiency and in the diagnosis of megaloblastic anemias.

1.MartÍ, R., LÓpez, L.C., and Hirano, M.Assessment of thymidine phosphorylase function: Measurement of plasma thymidine (and deoxyuridine) and thymidine phosphorylase activityMethods Mol. Biol.837121-133(2012) 2.Prusoff, W.H.Synthesis and biological activities of iododeoxyuridine, an analog of thymidineBiochim. Biophys. Acta.32(1)295-296(1959) 3.Bergstrom, D.E., and Ogawa, M.K.C-5 substituted pyrimidine nucleosides. 2. Synthesis via olefin coupling to organopalladium intermediates derived from uridine to 2’-deoxyuridineJ. Am. Chem. Soc.100(26)8106-8112(1978)